Non-genetic and genetic predictors of a superficial first basal cell carcinoma.

ABSTRACT:

Background

Several observational studies have suggested differences in the risk factor profile between patients with superficial basal cell carcinomas (BCCs) and non-superficial BCCs.

Objective

To test the reproducibility of previous study findings and to find new genetic and non-genetic predictors for patients with a superficial first BCC.

Methods

A total of 14.628 participants of northwestern European descent aged 45 years or older from a prospective population-based cohort study (Rotterdam Study) were linked with the Dutch Pathology Registry (PALGA) of whom 1528 were identified as BCC patients. After exclusion, 948 eligible BCC patients remained for further non-genetic analyses and 1014 for genetic analyses. We included 11 phenotypic, environmental and tumour-speci

SUBMITTER: Verkouteren JAC 

PROVIDER: S-EPMC6593991 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature