TypeLoader2: Automated submission of novel HLA and killer-cell immunoglobulin-like receptor alleles in full length.

ABSTRACT: The Immuno Polymorphism Database (IPD) databases provide global, curated repositories for information regarding polymorphisms of genes of the immune system, thereby generating immense value for the research and clinical communities. The advent of high-throughput genotyping in immunogenetics has led to dramatically growing numbers of heretofore unknown HLA and lately also killer-cell immunoglobulin-like receptor (KIR) alleles, which are to be curated and deposited in the IPD-IMGT/HLA and IPD-KIR databases, respectively. It is highly desirable that these novel alleles are characterised and submitted in full length, and that known alleles are extended to cover the complete gene sequence. However, the manual annotation and submission of sequences to European Molecular Biology Laboratory's Euro

SUBMITTER: Schone B 

PROVIDER: S-EPMC6594033 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature