Quantitative relationships of exposure to chrysotile asbestos and mesothelioma mortality.

ABSTRACT:

Background

While asbestos has long been known to cause mesothelioma, quantitative exposure-response data on the relation of mesothelioma risk and exposure to chrysotile asbestos are sparse.

Methods

Quantitative relationships of mortality from mesothelioma and pleural cancer were investigated in an established cohort of 5397 asbestos textile manufacturing workers in North Carolina, USA. Eligible workers were those employed between 1950 and 1973 with mortality follow-up through 2003. Individual exposure to chrysotile fibres was estimated on the basis of 3420 air samples covering the entire study period linked to work history records. Exposure coefficients adjusted for age, race, and time-related covariates were estimated by Poisson regression.

Results

Positive, statisti

SUBMITTER: Loomis D 

PROVIDER: S-EPMC6594234 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature