Quorum and Light Signals Modulate Acetoin/Butanediol Catabolism in Acinetobacter spp.

ABSTRACT: Acinetobacter spp. are found in all environments on Earth due to their extraordinary capacity to survive in the presence of physical and chemical stressors. In this study, we analyzed global gene expression in airborne Acinetobacter sp. strain 5-2Ac02 isolated from hospital environment in response to quorum network modulators and found that they induced the expression of genes of the acetoin/butanediol catabolism, volatile compounds shown to mediate interkingdom interactions. Interestingly, the acoN gene, annotated as a putative transcriptional regulator, was truncated in the downstream regulatory region of the induced acetoin/butanediol cluster in Acinetobacter sp. strain 5-2Ac02, and its functioning as a negative regulator of this cluster integrating quorum si

SUBMITTER: Tuttobene MR 

PROVIDER: S-EPMC6595428 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature