Organization of the Claustrum-to-Entorhinal Cortical Connection in Mice.

ABSTRACT: The claustrum, a subcortical structure situated between the insular cortex and striatum, is reciprocally connected with almost all neocortical regions. Based on this connectivity, the claustrum has been postulated to integrate multisensory information and, in turn, coordinate widespread cortical activity. Although studies have identified how sensory information is mapped onto the claustrum, the function of individual topographically arranged claustro-cortical pathways has been little explored. Here, we investigated the organization and function of identified claustro-cortical pathways in mice using multiple anatomical and optogenetic techniques. Retrograde and anterograde tracing demonstrated that the density of anterior claustrum-to-cortical projection differs substantially depending on t

SUBMITTER: Kitanishi T 

PROVIDER: S-EPMC6596572 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature