Oxidative post-translational modification of EXECUTER1 is required for singlet oxygen sensing in plastids.

ABSTRACT: Environmental information perceived by chloroplasts can be translated into retrograde signals that alter the expression of nuclear genes. Singlet oxygen (¹O₂) generated by photosystem II (PSII) can cause photo-oxidative damage of PSII but has also been implicated in retrograde signaling. We previously reported that a nuclear-encoded chloroplast FtsH2 metalloprotease coordinates ¹O₂-triggered retrograde signaling by promoting the degradation of the EXECUTER1 (EX1) protein, a putative ¹O₂ sensor. Here, we show that a ¹O₂-mediated oxidative post-translational modification of EX1 is essential for initiating ¹O₂-derived signaling. Specifically, the Trp643 residue in DUF3506 domain of EX

SUBMITTER: Dogra V 

PROVIDER: S-EPMC6597547 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature