FunSet: an open-source software and web server for performing and displaying Gene Ontology enrichment analysis.

ABSTRACT:

Background

Gene Ontology enrichment analysis provides an effective way to extract meaningful information from complex biological datasets. By identifying terms that are significantly overrepresented in a gene set, researchers can uncover biological features shared by genes. In addition to extracting enriched terms, it is also important to visualize the results in a way that is conducive to biological interpretation.

Results

Here we present FunSet, a new web server to perform and visualize enrichment analysis. The web server identifies Gene Ontology terms that are statistically overrepresented in a target set with respect to a background set. The enriched terms are displayed in a 2D plot that captures the semantic similarity between terms, with the option to cluster terms via

SUBMITTER: Hale ML 

PROVIDER: S-EPMC6598242 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature