A Decade On: Systematic Review of ClinicalTrials.gov Infectious Disease Trials, 2007-2017.

ABSTRACT:

Background

Registration of interventional trials of Food and Drug Administration-regulated drug and biological products and devices became a legal requirement in 2007; the vast majority of these trials are registered in ClinicalTrials.gov. An analysis of ClinicalTrials.gov offers an opportunity to define the clinical research landscape; here we analyze 10 years of infectious disease (ID) clinical trial research.

Methods

Beginning with 166 415 interventional trials registered in ClinicalTrials.gov from 2007-2017, ID trials were selected by study conditions and interventions. Relevance to ID was confirmed through manual review, resulting in 13 707 ID trials and 152 708 non-ID trials.

Results

ID-related trials represented 6.9%-9.9% of all trials with no significant trend

SUBMITTER: Jaffe IS 

PROVIDER: S-EPMC6598302 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature