Dynamic Modulation of Cortical Excitability during Visual Active Sensing.

ABSTRACT: Visual physiology is traditionally investigated by presenting stimuli with gaze held constant. However, during active viewing of a scene, information is actively acquired using systematic patterns of fixations and saccades. Prior studies suggest that during such active viewing, both nonretinal, saccade-related signals and "extra-classical" receptive field inputs modulate visual processing. This study used a set of active viewing tasks that allowed us to compare visual responses with and without direct foveal input, thus isolating the contextual eye movement-related influences. Studying nonhuman primates, we find strong contextual modulation in primary visual cortex (V1): excitability and response amplification immediately after fixation onset, transiting to suppression leading up to the ne

SUBMITTER: Barczak A 

PROVIDER: S-EPMC6598687 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature