Demonstration of velocity selective myocardial arterial spin labeling perfusion imaging in humans.

ABSTRACT:

Purpose

Transit delay is a potential source of error in cardiac arterial spin-labeled (ASL) in heart failure or with collateral circulation. This study demonstrates the feasibility of using transit delay insensitive velocity selective ASL and compares its performance with flow-sensitive alternating inversion recovery (FAIR) ASL.

Methods

Velocity selective labeling was achieved using an adiabatic BIR8 preparation. FAIR and velocity-selective ASL (VSASL) with various velocity cutoffs (V_C  = 10-40 cm/s) and labeling directions (anterior-posterior X, lateral-septal Y, and apical-basal Z) were carried out in 10 healthy volunteers (1F/9M age 23-30 y). Myocardial blood flow (MBF) and temporal signal-to-noise (TSNR) were measured.

Results

VSASL sensitivity to perfu

SUBMITTER: Jao TR 

PROVIDER: S-EPMC6598714 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature