The effect of aripiprazole once-monthly on personal and social functioning: post hoc analyses of acute and long-term studies.

ABSTRACT:

Objective

To evaluate the effect of aripiprazole once-monthly 400 mg (AOM 400; Abilify Maintena^®) on personal and social functioning in patients with schizophrenia in both the acute treatment and maintenance therapy settings.

Methods

Post hoc analyses were conducted on data from Study 291 (NCT01663532), a 12-week, randomized, double-blind, placebo-controlled trial conducted in patients who were experiencing an acute psychotic episode, and Study 248 (NCT00731549), a 52-week open-label extension of two randomized, controlled trials of AOM 400 as maintenance therapy. Assessment of functioning was made using the Personal and Social Performance (PSP) scale. In Study 291, results were stratified by age (≤35 years or >35 years).

Results

In Study 291, 340 patients

SUBMITTER: Peters-Strickland T 

PROVIDER: S-EPMC6598750 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature