Measuring the Burden of Schizophrenia Using Clinician and Patient-Reported Measures: An Exploratory Analysis of Construct Validity.

ABSTRACT:

Background

Various self-reported or clinician-reported (as a proxy) measures exist to quantify the burden of schizophrenia on patients. Evidence of the psychometric relationship between these measures to inform their practical use is limited.

Objectives

Our objective was to conduct an exploratory analysis of the construct validity of patient-reported (EQ-5D, SF-6D, WEMWBS, SQLS subscales of Psychosocial, Motivation, Symptoms) versus clinician-reported measures (PANSS, CGI-SCH, NSA-4, HoNOS-PbR) to inform future use of patient-reported measures for burden-of-illness assessment and/or economic evaluation.

Methods

In an adult patient population with schizophrenia, construct validity was assessed in relation to convergent and known-group validity. Convergent validity was

SUBMITTER: Franklin M 

PROVIDER: S-EPMC6599186 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature