Comparability of biological aging measures in the National Health and Nutrition Examination Study, 1999-2002.

ABSTRACT:

Background

Biological processes of aging are thought to be modifiable causes of many different chronic diseases. Measures of biological aging could provide sensitive endpoints for studies of risk factors hypothesized to shorten healthy lifespan and/or interventions that extend it. But uncertainty remains about how to measure biological aging and if proposed measures assess the same thing.

Method

We tested four proposed measures of biological aging that could be quantified with available data from the National Health and Nutrition Examination Survey (NHANES), Klemera-Doubal method (KDM) Biological Age, homeostatic dysregulation, Levine Method (LM) Biological Age, and leukocyte telomere length.

Results

We analyzed data collected during 1999-2002, when all four biologica

SUBMITTER: Hastings WJ 

PROVIDER: S-EPMC6599717 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature