Maternal obesity and the human milk metabolome: associations with infant body composition and postnatal weight gain.

ABSTRACT:

Background

Maternal obesity is a risk factor for childhood obesity; this is a major public health concern given that ∼40% of pregnant women are either overweight or obese. Whether differences in milk composition in lean compared with obese women contribute to childhood obesity is unclear.

Objectives

We aimed to analyze relationships between maternal obesity and human milk metabolites, infant body composition, and postnatal weight gain.

Methods

This was a prospective study in which mothers intending to breastfeed exclusively, and their newborn infants, were enrolled at delivery (n = 35 mother-infant pairs). We excluded mothers with diabetes, other medical conditions, or pregnancy complications. Participants were grouped by maternal prepregnancy BMI <25 (lean) or ≥25 kg

SUBMITTER: Isganaitis E 

PROVIDER: S-EPMC6599743 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature