Association between Circulating Irisin and C-Reactive Protein Levels: A Systematic Review and Meta-Analysis.

ABSTRACT: BACKGROUND:Although previous studies have demonstrated that irisin plays an anti-inflammatory role in the body, conflicting results have been reported regarding the correlation between serum levels of irisin and C-reactive protein (CRP). The present meta-analysis was conducted to further investigate the correlation between irisin and CRP levels. METHODS:We systematically searched PubMed, the Cochrane Library, Web of Science, Embase, SCOPUS, and Ovid to retrieve studies assessing the correlation between irisin and CRP levels. Meta-analyses were performed using a random-effects model, and the I² index was used to evaluate heterogeneity. RESULTS:Of the 428 studies that were initially found, 14 studies with 2,530 participants met the inclusion criteria for the meta-analysis. The pooled effect

SUBMITTER: Eslampour E 

PROVIDER: S-EPMC6599904 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature