Prolapse and regurgitation of the four heart valves in a patient with Ehlers-Danlos Syndrome: a case report.

ABSTRACT: The Ehlers-Danlos Syndrome (EDS) is part of a group of connective tissue diseases that affect the synthesis and processing of collagen leading to alterations in the structure of many tissues and organs. Herein, we reported a case of a patient with prolapse of the four cardiac valves. Non-significant regurgitation of the mitral, aortic, and tricuspid valves was observed. The pulmonary regurgitation (PR) was considered significant. Dilatation of the right ventricle with preserved systolic function was also noted. A cardiac magnetic resonance confirmed the findings of the echocardiogram and determined a severe PR (regurgitant fraction of 41%). The physical examination revealed hyperlaxity of the joints, skin hyperelasticity, defects in wound healing, and abdominal hernias suggesting EDS. The

SUBMITTER: Chango Azanza DX 

PROVIDER: S-EPMC6601149 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature