Depression and cause-specific mortality in an ethnically diverse cohort from the UK: 8-year prospective study.

ABSTRACT:

Background

Depression is associated with increased mortality, however, little is known about its variation by ethnicity.

Methods

We conducted a cohort study of individuals with ICD-10 unipolar depression from secondary mental healthcare, from an ethnically diverse location in southeast London, followed for 8 years (2007-2014) linked to death certificates. Age- and sex- standardised mortality ratios (SMRs), with the population of England and Wales as a standard population were derived. Hazard ratios (HRs) for mortality were derived through multivariable regression procedures.

Results

Data from 20 320 individuals contributing 91 635 person-years at risk with 2366 deaths were used for analyses. SMR for all-cause mortality in depression was 2.55(95% CI 2.45-2.65), with si

SUBMITTER: Das-Munshi J 

PROVIDER: S-EPMC6601358 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature