High-Resolution In Vivo Fundus Angiography using a Nonadaptive Optics Imaging System.

ABSTRACT:

Purpose

We provide a proof of concept for the detailed characterization of retinal capillary features and surrounding photoreceptor mosaic using a customized nonadaptive optics angiography imaging system.

Methods

High-resolution fluorescein angiography (FFA) and/or indocyanine green angiography (ICGA) images were obtained using a modified Heidelberg retina angiograph (HRA2) device with a reduced scan angle enabling 3° field of view. Colocalized images of the photoreceptor mosaic also were captured in vivo using the same instrument. Visibility of vascular subbranches were compared between high-resolution images and conventional fundus angiography (FA) with a 30° field of view.

Results

High-resolution angiographic and infrared images (3° × 3° field of view, a 10-fold ma

SUBMITTER: Okada M 

PROVIDER: S-EPMC6602143 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature