EPIC-TABSAT: analysis tool for targeted bisulfite sequencing experiments and array-based methylation studies.

ABSTRACT: DNA methylation is one of the major epigenetic modifications and has frequently demonstrated its suitability as diagnostic and prognostic biomarker. In addition to chip and sequencing based epigenome wide methylation profiling methods, targeted bisulfite sequencing (TBS) has been established as a cost-effective approach for routine diagnostics and target validation applications. Yet, an easy-to-use tool for the analysis of TBS data in combination with array-based methylation results has been missing. Consequently, we have developed EPIC-TABSAT, a user-friendly web-based application for the analysis of targeted sequencing data that additionally allows the integration of array-based methylation results. The tool can handle multiple targets as well as multiple sequencing files in parallel and

SUBMITTER: Krainer J 

PROVIDER: S-EPMC6602470 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature