Liver Stiffness Measurement With FibroScan: Use the Right Probe in the Right Conditions!

ABSTRACT:

Introduction

FibroScan's M and XL probes give significantly different results, which could lead to misevaluation of liver fibrosis if the correct probe is not chosen. According to the manufacturer, the M probe should be used when the skin-liver capsule distance (SCD) is <25 mm, and the XL probe should be used when SCD is ≥25 mm. We aimed at validating this recommendation and defining the conditions of use for FibroScan probes in clinical practice.

Methods

Four hundred thirty-nine patients with biopsy-proven chronic liver disease were included. Of them, 382 had successful examinations with both M and XL probes. Advanced fibrosis was defined as Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) F ≥3 or Metavir F ≥2.

Results

In a same patient, XL probe res

SUBMITTER: Berger A 

PROVIDER: S-EPMC6602786 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature