Identification of Plasma Lipid Metabolites Associated with Nut Consumption in US Men and Women.

ABSTRACT:

Background

Intake of nuts has been inversely associated with risk of type 2 diabetes and cardiovascular disease, partly through inducing a healthy lipid profile. How nut intake may affect lipid metabolites remains unclear.

Objective

The aim of this study was to identify the plasma lipid metabolites associated with habitual nut consumption in US men and women.

Methods

We analyzed cross-sectional data from 1099 participants in the Nurses' Health Study (NHS), NHS II, and Health Professionals Follow-up Study. Metabolic profiling was conducted on plasma by LC-mass spectrometry. Nut intake was estimated from food-frequency questionnaires. We included 144 known lipid metabolites that had CVs ≤25%. Multivariate linear regression was used to assess the associations of nut cons

SUBMITTER: Malik VS 

PROVIDER: S-EPMC6602895 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature