The Signal Transduction Protein P_II Controls Ammonium, Nitrate and Urea Uptake in Cyanobacteria.

ABSTRACT: P_II signal transduction proteins are widely spread among all domains of life where they regulate a multitude of carbon and nitrogen metabolism related processes. Non-diazotrophic cyanobacteria can utilize a high variety of organic and inorganic nitrogen sources. In recent years, several physiological studies indicated an involvement of the cyanobacterial P_II protein in regulation of ammonium, nitrate/nitrite, and cyanate uptake. However, direct interaction of P_II has not been demonstrated so far. In this study, we used biochemical, molecular genetic and physiological approaches to demonstrate that P_II regulates all relevant nitrogen uptake systems in Synechocystis sp. strain PCC 6803: P_II controls ammonium uptake by interacting

SUBMITTER: Watzer B 

PROVIDER: S-EPMC6603209 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature