Serum markers for early detection of patients with mesenteric ischemia after cardiac surgery.

ABSTRACT:

Objective

Mesenteric ischemia (MESI) is a rare but often fatal complication in patients after cardiac surgery. Non-specific clinical symptoms and lack of specific laboratory parameters complicate the diagnosis. We evaluated potential serum markers for MESI in cardiac surgery patients.

Methods

Between March and October 2012, serial serum samples of 567 elective cardiac surgery patients were collected 1, 24, and 48 h after the operation, and concentrations of potential markers for MESI [α-glutathione-S-transferase (αGST), intestinal fatty-acid-binding protein (iFABP), and D-lactate] were measured retrospectively. In patients requiring laparotomy, blood samples obtained 72, 48, 24, and 12 h before the laparotomy were additionally measured and compared to all other patients (con

SUBMITTER: Dohle DS 

PROVIDER: S-EPMC6604586 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature