Enhanced passive surveillance of influenza vaccination in England, 2016-2017- an observational study using an adverse events reporting card.

ABSTRACT: Influenza is a major public health burden, mainly prevented by vaccination. Recommendations on influenza vaccine composition are updated annually and constant benefit-risk monitoring is therefore needed. We conducted near-real-time enhanced passive surveillance (EPS) for the influenza vaccine, Fluarix Tetra, according to European Medicines Agency guidance, in 10 volunteer general practices in England using Fluarix Tetra as their principal influenza vaccine brand, from 1-Sep to 30-Nov-2016. The EPS method used a combination of routinely collected data from electronic health records (EHR) and a customized adverse events reporting card (AERC) distributed to participants vaccinated with Fluarix Tetra. For participants vaccinated with a different influenza vaccine, data were derived exclusively

SUBMITTER: de Lusignan S 

PROVIDER: S-EPMC6605873 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature