Genomic Comparison of Lactobacillus helveticus Strains Highlights Probiotic Potential.

ABSTRACT: Lactobacillus helveticus belongs to the large group of lactic acid bacteria (LAB), which are the major players in the fermentation of a wide range of foods. LAB are also present in the human gut, which has often been exploited as a reservoir of potential novel probiotic strains, but several parameters need to be assessed before establishing their safety and potential use for human consumption. In the present study, six L. helveticus strains isolated from natural whey cultures were analyzed for their phenotype and genotype in exopolysaccharide (EPS) production, low pH and bile salt tolerance, bile salt hydrolase (BSH) activity, and antibiotic resistance profile. In addition, a comparative genomic investigation was performed between the six newly sequenced strains and the 51 pu

SUBMITTER: Fontana A 

PROVIDER: S-EPMC6606699 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature