Quantifying the impact of genes on body mass index during the obesity epidemic: longitudinal findings from the HUNT Study.

ABSTRACT:

Objectives

To study the trajectories of body mass index (BMI) in Norway over five decades and to assess the differential influence of the obesogenic environment on BMI according to genetic predisposition.

Design

Longitudinal study.

Setting

General population of Nord-Trøndelag County, Norway.

Participants

118 959 people aged 13-80 years who participated in a longitudinal population based health study (Nord-Trøndelag Health Study, HUNT), of whom 67 305 were included in analyses of association between genetic predisposition and BMI.

Main outcome measure

BMI.

Results

Obesity increased in Norway starting between the mid-1980s and mid-1990s and, compared with older birth cohorts, those born after 1970 had a substantially higher BMI already in young adul

SUBMITTER: Brandkvist M 

PROVIDER: S-EPMC6607203 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature