Mycobacterium decipiens sp. nov., a new species closely related to the Mycobacterium tuberculosis complex.

ABSTRACT: Two mycobacterial strains with close similarity to the Mycobacterium tuberculosis complex (MTBC) were isolated from cutaneous lesions of patients in the USA and Italy. At the phenotypic level, similarities to the MTBC included slow growth rate, rough morphotype of the unpigmented colonies and nearly identical high-performance liquid chromatography profiles of mycolic acids. In contrast to the MTBC, the strains were niacin- and nitrate-negative, and catalase-positive both at 68 °C and in semi-quantitative tests. The clinical isolates were more closely related to M. tuberculosis than to any other known mycobacterium and scored positive with commercial DNA probes (Hologic AccuProbe M. tuberculosis). Both average nucleotide identity and genome-to-genome distance suggested the strains are diffe

SUBMITTER: Brown-Elliott BA 

PROVIDER: S-EPMC6607433 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature