Real-world treatment patterns of sacubitril/valsartan: a longitudinal cohort study in Germany.

ABSTRACT:

Aims

To analyse real-world treatment patterns of sacubitril/valsartan (sac/val) using data from a pharmacy database in Germany.

Methods and results

A retrospective cohort study of 26 191 adult patients (aged ≥ 18 years) in the IMS® longitudinal prescriptions database in Germany who were dispensed sac/val from January 2016 to June 2017 was conducted. The analysis included sac/val dose titration assessed in the 6 months from first sac/val prescription; prescriptions of concomitant cardiovascular medications in the 6 months pre- and post-index and compliance and persistence during 12 months post-index. Two-thirds of patients were prescribed the lowest sac/val dose of 50 mg twice daily (b.i.d.) at index and up-titration during the first 6 months was attempted in 41% of these pat

SUBMITTER: Wachter R 

PROVIDER: S-EPMC6607491 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature