Epicardial fat in heart failure patients with mid-range and preserved ejection fraction.

ABSTRACT:

Aims

Adipose tissue and inflammation may play a role in the pathophysiology of patients with heart failure (HF) with mildly reduced or preserved ejection fraction. We therefore investigated epicardial fat in patients with HF with preserved (HFpEF) and mid-range ejection fraction (HFmrEF), and related this to co-morbidities, plasma biomarkers and cardiac structure.

Methods and results

A total of 64 HF patients with left ventricular ejection fraction >40% and 20 controls underwent routine cardiac magnetic resonance examination. Epicardial fat volume was quantified on short-axis cine stacks covering the entire epicardium and was related to clinical correlates, biomarkers associated with inflammation and myocardial injury, and cardiac function and contractility on cardiac magnet

SUBMITTER: van Woerden G 

PROVIDER: S-EPMC6607508 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature