Phrenic nerve stimulation to treat patients with central sleep apnoea and heart failure.

ABSTRACT:

Aims

The presence of central sleep apnoea (CSA) is associated with poor prognosis in patients with heart failure (HF). The aim of this analysis was to evaluate if using phrenic nerve stimulation to treat CSA in patients with CSA and HF was associated with changes in HF-specific metrics.

Methods and results

All patients randomized in the remedē System Pivotal Trial and identified at baseline with HF were included (n = 96). Effectiveness data from treatment and former control groups were pooled based on months since therapy activation. Changes from baseline to 6 and 12 months in sleep metrics, Epworth Sleepiness Scale, patient global assessment health-related quality of life, Minnesota Living with Heart Failure Questionnaire (MLHFQ), and echocardiographic parameters are report

SUBMITTER: Costanzo MR 

PROVIDER: S-EPMC6607512 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature