Ecological and Socioeconomic Predictors of Transmission Assessment Survey Failure for Lymphatic Filariasis.

ABSTRACT: The transmission assessment survey (TAS) is recommended to determine whether cessation of mass drug administration (MDA) for lymphatic filariasis (LF) is warranted. Ministries of health typically implement TASs in evaluation units (EUs) that have had more than five rounds of annual MDA. Under TAS guidelines, sample size calculations determine a decision value: if the number of individuals testing positive exceeds this threshold, then MDA continues in the EU. The objective of this study was to determine whether fine scale geospatial covariates could be used to identify predictors of TAS failure. We geo-referenced 746 TAS EUs, of which 65 failed and extracted geospatial covariates using R to estimate odds of failure. We implemented stepwise backward elimination to select covariates for inclu

SUBMITTER: Goldberg EM 

PROVIDER: S-EPMC6609191 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature