Is the Oral Microbiome Associated with Blood Pressure in Older Women?

ABSTRACT:

Introduction

A possible role of the oral microbiome, specifically oral nitrate reducing flora, in blood pressure (BP) homeostasis, if proven etiologic in nature, could lead to novel mechanism-based therapy to improve hypertension prevention and control.

Aim

This cross-sectional study characterized and compared the oral microbiome between four study groups based on BP status among 446 postmenopausal women aged 53-82 years.

Methods

Three study groups were not taking hypertension medication and were separated based on BP, as follows: normal BP (systolic < 120 and diastolic < 80; N = 179), elevated BP/Stage I hypertension (systolic 120-139 or diastolic 80-90; N = 106), Stage II hypertension (systolic > 140 or diastolic > 90; N = 42). The forth group consisted of anyone ta

SUBMITTER: Gordon JH 

PROVIDER: S-EPMC6610722 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature