Low concordance of oral and genital HPV infection among male patients with sexually transmitted infections in Vietnam.

ABSTRACT:

Background

Human papillomavirus (HPV) causes cancers in men, including penile, anal, and oropharyngeal cancers. This cross-sectional study aimed to investigate the prevalence, the genotypes, and the risk factors of HPV infections in the oral cavity, compared to those in the genitals, among males diagnosed with sexually transmitted infections (STIs) in Vietnam.

Methods

Oral, urinary, penile, and urethral samples were collected from 198 male Vietnamese patients with STIs (median age 31.0 years, range 17-68). HPV DNA was isolated and amplified with PCR, with modified and/or original GP5⁺/GP6⁺ primers. Samples were genotyped with a gene array assay and/or population sequencing.

Results

HPV DNA was detected in 69 (34.8%) of 198 patients. Of these, 16

SUBMITTER: Le HHL 

PROVIDER: S-EPMC6610792 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature