A novel knowledge-derived data potentizing method revealed unique liver cancer-associated genetic variants.

ABSTRACT:

Background

Next-generation sequencing (NGS) has been advancing the progress of detection of disease-associated genetic variants and genome-wide profiling of expressed sequences over the past decade. NGS enables the analyses of multiple regions of a genome in a single reaction format and has been shown to be a cost-effective and efficient tool for root-cause analysis of disease and optimization of treatment. NGS has been leading global efforts to device personalized and precision medicine (PM) in clinical practice. The effectiveness of NGS for the aforementioned applications has been proven unequivocal for multifactorial diseases like cancer. However, definitive prediction of cancer markers for all types of diseases and for global populations still remains highly rewarding because o

SUBMITTER: Sultana N 

PROVIDER: S-EPMC6610914 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature