Ventricle-specific epicardial pressures as a means to optimize direct cardiac compression for circulatory support: A pilot study.

ABSTRACT: Direct cardiac compression (DCC) holds enormous potential as a safe and effective means to treat heart failure patients who require long-term, or even permanent, biventricular support. However, devices developed to date are not tuned to meet the individual compression requirements of the left and right ventricles, which can differ substantially. In this paper, a systematic study examining the relationship, range, and effect of independent pressures on the left and right epicardial surfaces of a passive human heart model was performed as a means to optimize cardiac output via DCC support. Hemodynamic and tissue deformation effects produced by varying epicardial compressions were examined using finite element analysis. Results indicate that 1) designing a direct cardiac compression pump that

SUBMITTER: Han J 

PROVIDER: S-EPMC6611657 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature