European follow-up of incorrect biomarker results for colorectal cancer demonstrates the importance of quality improvement projects.

ABSTRACT: Biomarker analysis for colorectal cancer has been shown to be reliable in Europe with 97% of samples tested by EQA participants to be correctly classified. This study focuses on errors during the annual EQA assessment. The aim was to explore the causes and actions related to the observed errors and to provide feedback and assess any improvement between 2016 and 2017. An electronic survey was sent to all laboratories with minimum one genotyping error or technical failure on ten tumor samples. A workshop was organized based on 2016 survey responses. Improvement of performance in 2017 was assessed for returning participants (n = 76), survey respondents (n = 13) and workshop participants (n = 4). Survey respondents and workshop participants improved in terms of (maximum) analysis score, succes

SUBMITTER: Keppens C 

PROVIDER: S-EPMC6611891 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature