Medical Cannabinoids for Cancer Cachexia: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objectives

Cancer cachexia (CCA) is an intractable and ineffective metabolic syndrome that attacks 50-80% of cancer patients. It reduces patient's life quality, affects the efficacy of treatment, and then increases their mortality; however, there are no established therapeutic strategies for CCA in the world. In this study, we assess the positive and negative effects of cannabinoid in the treatment of CCA.

Methods

We searched the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library, MEDLINE, EMBASE, Web of Science, and PubMed up to December 2017.

Results

Of the 256 screened studies, three studies with a total of 592 participants were included. Compared with placebo, cannabinoid increased the appetite (MD 0.27, 95% CI -0.51 to 1.04; n= 3) bu

SUBMITTER: Wang J 

PROVIDER: S-EPMC6612387 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature