The prognostic impact of age in different molecular subtypes of breast cancer: a population-based study.

ABSTRACT:

Background

The aim of current study was to use competing risk model to calculate the potential differences that age played in the prognosis of different breast cancer subtypes.

Methods

The cohort was selected from Surveillance, Epidemiology, and End Results (SEER) program. The cumulative incidences of death (CID) was assessed for breast cancer caused deaths and other causes of mortality. The multivariate Cox proportional hazards regression model and the multivariate subdistribution hazard (SH) model were used to evaluate the prognostic value of age in different breast cancer subtypes.

Results

We involved 33,968 breast cancer patients into our cohort. We found older patients had worse overall survival (OS) than young patients in hormone receptor positive and human epid

SUBMITTER: Dai D 

PROVIDER: S-EPMC6612417 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature