Association Between Prediabetes/Diabetes and Asthma Exacerbations in a Claims-Based Obese Asthma Cohort.

ABSTRACT:

Background

Metabolic dysfunction may contribute to worsened asthma in obesity. The relationship between prediabetes and diabetes, metabolic conditions more common in obesity, and asthma outcomes is not well characterized.

Objective

We sought to determine the association between prediabetes/diabetes and asthma exacerbations in an obese asthma cohort.

Methods

A retrospective cohort of US obese adults with asthma, aged 18-64, was created from a claims-based health services database spanning 2010 to 2015. Individuals with a hemoglobin A1c (HbA1c) measurement were identified, categorized as within normal (<5.6%), prediabetes (5.7% to 6.4%), and diabetes (≥6.5%) ranges. Exacerbations, defined as asthma-related hospitalization, emergency department visit, or corticosteroid p

SUBMITTER: Wu TD 

PROVIDER: S-EPMC6612446 | biostudies-literature | 2019 Jul - Aug

REPOSITORIES: biostudies-literature