Early Pregnancy Hemoglobin A1C and Pregnancy Outcomes: A Population-Based Study.

ABSTRACT:

Objective

Women with prediabetes are identified from screening for overt diabetes in early pregnancy, but the clinical significance of prediabetes in pregnancy is unclear. We examined whether prediabetes in early pregnancy was associated with risks of adverse outcomes.

Study design

We conducted a retrospective cohort study of pregnant women enrolled in Kaiser Permanente Washington from 2011 to 2014. Early pregnancy hemoglobin A1C (A1C) values, covariates, and outcomes were ascertained from electronic medical records and state birth certificates. Women with prediabetes (A1C of 5.7-6.4%) were compared with those with normal A1C levels (<5.7%) for risk of gestational diabetes mellitus (GDM) and other outcomes including preeclampsia, primary cesarean delivery, induction of labor

SUBMITTER: Chen L 

PROVIDER: S-EPMC6612540 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature