Exploring the Impact of Adding a Respiratory Dimension to the EQ-5D-5L.

ABSTRACT: Objectives. To evaluate the impact of adding a respiratory dimension (a bolt-on dimension) to the EQ-5D-5L health state valuations. Methods. Based on extensive regression and principal component analyses, 2 respiratory bolt-on candidates were formulated: R1, limitations in physical activities due to shortness of breath, and R2, breathing problems. Valuation interviews for the selected bolt-ons were performed with a representative sample from the Dutch general public using the standardized interview protocol and software of the EuroQol group. Hybrid models based on the combined time-tradeoff (TTO) and discrete choice experiment (DCE) data were estimated to assess whether the 5 levels of the respiratory bolt-on led to significant changes in utility values. Results. For e

SUBMITTER: Hoogendoorn M 

PROVIDER: S-EPMC6613181 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature