Quadruple versus triple combination antiretroviral therapies for treatment naive people with HIV: systematic review and meta-analysis of randomised controlled trials.

ABSTRACT:

Objective

To evaluate the effects of four drug (quadruple) versus three drug (triple) combination antiretroviral therapies in treatment naive people with HIV, and explore the implications of existing trials for clinical practice and research.

Design

Systematic review and meta-analysis of randomised controlled trials.

Data sources

PubMed, EMBASE, CENTRAL, Web of Science, and the Cumulative Index to Nursing and Allied Health Literature from March 2001 to December 2016 (updated search in PubMed and EMBASE up to June 2018); and reference lists of eligible studies and related reviews.

Study selection

Randomised controlled trials comparing quadruple with triple combination antiretroviral therapies in treatment naive people with HIV and evaluating at least one effecti

SUBMITTER: Feng Q 

PROVIDER: S-EPMC6613201 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature