Statistical shape modeling of femur shape variability in female patients with hip dysplasia.

ABSTRACT: Although increasing evidence suggests that abnormal femur geometry in developmental dysplasia of the hip (DDH) may contribute to intra-articular damage and the development of hip osteoarthritis, a comprehensive 3D description of femoral abnormalities in DDH remains incomplete. Statistical shape modeling (SSM) was used to quantify three-dimensional (3D) geometric variation among femurs in female patients with DDH and control subjects. SSM correspondence points (n = 8,192) were placed on each femur using a gradient descent energy function to derive mean DDH and control femoral shapes and principal component analysis (PCA) was then used to describe shape variation. PCA results were associated with common 2D radiographic measures of femur shape using general linear models. For patients with DD

SUBMITTER: Gaffney BMM 

PROVIDER: S-EPMC6613213 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature