Pre-pregnancy maternal fasting plasma glucose levels in relation to time to pregnancy among the couples attempting first pregnancy.

ABSTRACT:

Study question

What is the relationship between pre-pregnancy maternal glucose levels and fecundability in Chinese couples?

Summary answer

Elevated pre-pregnancy maternal glucose levels were associated with fecundability, as reflected by prolonged time to pregnancy (TTP) among the couples with no prior gravidity.

Study design, size, duration

Based on the National Free Pre-conception Check-up Projects supported by the Chinese government, 2 226 048 eligible couples attempting first pregnancy and participating in the project from 2015 to 2016 were included. They were followed-up for 1 year or until they reported pregnancy.

Participants/materials, settings, methods

The Kaplan-Meier method was used to estimate the cumulative pregnancy rate in each menstrual cycle, a

SUBMITTER: Zhao J 

PROVIDER: S-EPMC6613343 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature