Ontology highlight
ABSTRACT:
SUBMITTER: Alves JM
PROVIDER: S-EPMC6613634 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Stem cell reviews and reports 20190201 1
The bioactive peptide bradykinin obtained from cleavage of precursor kininogens activates the kinin-B2 receptor functioning in induction of inflammation and vasodilatation. In addition, bradykinin participates in kidney and cardiovascular development and neuronal and muscle differentiation. Here we show that kinin-B2 receptors are expressed throughout differentiation of murine C2C12 myoblasts into myotubes. An autocrine loop between receptor activation and bradykinin secretion is suggested, sinc ...[more]