Thermal Memory Based Photoacoustic Imaging of Temperature.

ABSTRACT: Temperature mapping is essential in many biomedical studies and interventions to precisely control the tissue's thermal conditions for optimal treatment efficiency and minimal side effects. Based on the Grüneisen parameter's temperature dependence, photoacoustic (PA) imaging can provide relative temperature measurement, but it has been traditionally challenging to measure absolute temperatures without knowing the baseline temperature, especially in deep tissues with unknown optical and acoustic properties. Here, we report a new thermal-energy-memory-based photoacoustic thermometry (TEMPT). By illuminating the tissue with a burst of nanosecond laser pulses, TEMPT exploits the temperature dependence of the thermal energy lingering, which is probed by the corresponding PA signals acquired wit

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC6613656 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature