Rapid, High-Resolution, Label-Free, and 3-Dimensional Imaging to Differentiate Colorectal Adenomas and Non-Neoplastic Polyps With Micro-Optical Coherence Tomography.

ABSTRACT:

Introduction

"Resect and discard" paradigm is one of the main strategies to deal with colorectal diminutive polyps after optical diagnosis. However, there are risks that unrecognized potentially malignant lesions are discarded without accurate diagnosis. The purpose of this study is to validate the potential of micro-optical coherence tomography (μOCT) to improve the diagnostic accuracy of colorectal lesions and help endoscopists make better clinical decision without additional pathology costs.

Methods

Fresh tissue samples were obtained from patients with colorectal polyps or colorectal cancer who received endoscopic therapy or laparoscopic surgery. These samples were instantly imaged by μOCT and then sent to pathological evaluation. Then, μOCT images were compared with corr

SUBMITTER: Ding Q 

PROVIDER: S-EPMC6613865 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature