Associations of prenatal exposure to impaired glucose tolerance with eating in the absence of hunger in early adolescence.

ABSTRACT:

Objective

Exposure to impaired gestational glucose tolerance has been shown to have sex-specific associations with offspring obesity risk, perhaps by affecting the development of appetite regulation. We examined the extent to which prenatal exposure to impaired glucose tolerance was associated with eating in the absence of hunger (EAH) in early adolescent offspring, and in turn, whether EAH was cross-sectionally associated with body composition.

Methods

We included data from 1097 adolescents participating in Project Viva, a pre-birth longitudinal cohort. We obtained the results of two-stage prenatal glycemic screening (50 g glucose challenge test, followed if abnormal by 100 g oral glucose tolerance test) at 26-28 weeks of gestation, and categorized mothers as having normal

SUBMITTER: Derks IPM 

PROVIDER: S-EPMC6614016 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature