Ontology highlight
ABSTRACT:
SUBMITTER: Virag L
PROVIDER: S-EPMC6614175 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Redox biology 20190628
Activated macrophages play a central role in both the development and resolution of inflammation. These immune cells need to be functional in harmful conditions with high levels of reactive oxygen and nitrogen species that can damage their basic cell components, which may alter their metabolism. An excessive accumulation of these cell alterations drives macrophages inexorably to cell death, which has been associated to the development of several inflammatory diseases and even with aging in a pro ...[more]