Meta-analysis of Calibration, Discrimination, and Stratum-Specific Likelihood Ratios for the CRB-65 Score.

ABSTRACT:

Background

The CRB-65 score is recommended as a decision support tool to help identify patients with community-acquired pneumonia (CAP) who can safely be treated as outpatients.

Objective

To perform an updated meta-analysis of the accuracy, discrimination, and calibration of the CRB-65 score using a novel approach to calculation of stratum-specific likelihood ratios.

Design

Meta-analysis of accuracy, discrimination, and calibration.

Methods

We searched PubMed, Google, previous systematic reviews, and reference lists of included studies. Data was abstracted and quality assessed in parallel by two investigators. The quality assessment used an adaptation of the TRIPOD and PROBAST criteria. Measures of discrimination, calibration, and stratum-specific likelihood ra

SUBMITTER: Ebell MH 

PROVIDER: S-EPMC6614215 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature